In 1989 Jawaharlal Nehru Technological University established a number of Centers for Excellence to form a strong academic nucleus. They started functioning from 1991 under the Institute of Science and Technology (IST). IST was located in the heart of the twin cities of Hyderabad & Secunderabad. Now being located in the Campus which is also the Head quarters of JNT University, IST enjoys certain facilities. As any Technological upgradation within J.N.T.U. starts with IST. The location of the campus provides an academic environment and promotes learning.
Centre for Biotechnology Centre for Environment, Centre for Nanoscience and Technology, Centre for Pharmaceutical sciences, Centre for Spatial Information Technology, Centre for Water Resources are the constituent units of the institution.